KMID : 0616120230540020053
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Korean Journal of Pharmacognosy 2023 Volume.54 No. 2 p.53 ~ p.60
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Antioxidant Constituents of Athyrium acutipinnulum
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Park Hye-Jin
Ru Se-Hwan Yeon Sang-Won Ayman Turk Lee Sol-Ip Lee Hak-Hyun Hwang Bang-Yeon Lee Mi-Kyeong
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Abstract
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Athyrium acutipinnulum, called as Ulleungdo ladyfern (Seom-go-sa-ri), is a native plant of South Korea. A. acutipinnulum has been consumed as foods and also traditionally used for the treatment of epilepsy, gonorrhea and nerve disorder. The methanolic extract and EtOAc soluble fraction of A. acutipinnulum showed the antioxidant activity. Fractionation using various chromatographic techniques resulted in the isolation of 13 compounds. The structures were elucidated on the basis of spectroscopic methods as seven phenolic compounds, methyl 2-hydroxy-3-phenylpropanoate (1), protocatechualdehyde (2), caffeic acid (3), trans-p-coumaric acid (4), (-)-4-E-caffeoyl-L-threonic acid (5), 5-O-caffeoyl shikimic acid (6) and 5-O-caffeoyl quinic acid (7), three flavonoids, quercetin 3-O-¥â-glucoside (8), naringenin-7-O-¥â-glucoside (9) and sutchenoside A (10), two steroids, ponasterone A (11) and ecdysone (12) and a coumarin, esculetin (13). Among them, compounds 5 and 10 were first reported from Athyrium spp and compounds 2, 5, 6 and 7 showed the antioxidant activity.
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KEYWORD
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Athyrium acutipinnulum, Phenolic compounds, Flavonoid, Steroid, Antioxidant activity
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